Lyophilization also called as freeze drying is a process of
dehydration of samples, commonly used to preserve perishable substances. In
pharmaceutical industries, it is used to concentrate and stabilize products
into powder form. The process consists of four stages- lyophilization
pretreatment, freezing the compound, primary drying process, secondary drying.
Pretreating the products includes concentrating the product and formulation to
increase the surface area. Once the product is pretreated, it is frozen using
methanol or liquid nitrogen. At this stage, the compound is cooled below its
triple point which is the lowest temperature at which the vapor, liquid and
solid state co-exist. In the next stage of primary drying, the pressure is
reduced so that water in the compound sublimates. In the last stage, the
unfrozen water molecules are removed by increasing the temperature to near 0
degrees and lowering pressure for desorption.
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Lyophilization is an effective preservation process and
stabilization of compounds such as proteins, peptides, vaccines, blood
fractions, enzymes, microbes, nutraceuticals and other biopharmaceutical
products. They help in extending the shelf life while maintaining the functionality
and integrity of the biomolecules. Due to reduction of storage space and
weight, they also make the handling easier and avoid the need of cold storage.
Lyophilization market can be segmented based on product type
as follows:
- Lyophilization units
- Manifold freeze dryer
- Rotary freeze dryer
- Tray style freeze dryer
- Lyophilization services
The lyophilization market will be driven by its wide scope
of application, the advances in the pharmaceutical industry such as new drug
discovery and technological advances in the lyophilization methods such as
computer controlled process and automation in loading and unloading by
robotics. These augmentations will make the overall process easier and will
help in expanding the scope of application. The lyophilization instruments are
expensive and high electricity consumption unit. Apart from these factors the
process time for lyophilization is also long. But considering the merits, the
restraints do not drastically affect the market growth.
Some of the key players in the lyophilization units market
are ABB Ltd., W.L. Gore & Associates, Inc. and GEA Niro while
Lyophilization Technology, Inc., GenScript, Inc. Irvine Pharmaceutical Services
are some of the pyophilization services providers.
This research report analyzes this market depending on its
market segments, major geographies, and current market trends.
Geographies
analyzed under this research report include
- North America
- Asia Pacific
- Europe
- Rest of the World
This report provides comprehensive analysis of
- Market growth drivers
- Factors limiting market growth
- Current market trends
- Market structure
- Market projections for upcoming years
This report is a complete study of current trends in the
market, industry growth drivers, and restraints. It provides market projections
for the coming years. It includes analysis of recent developments in
technology, Porter’s five force model analysis and detailed profiles of top
industry players. The report also includes a review of micro and macro factors
essential for the existing market players and new entrants along with detailed
value chain analysis.
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